Human Mammary Epithelial Cell Line

To overcome this problem we have developed a cell line that was immortalized using defined genetic elements and we have characterized this immortalized non tumorigenic human mammary epithelial cell line to establish it as a potential model system.

Human mammary epithelial cell line.

Human mammary cell types generated. A mammary gland is an exocrine gland in humans and other mammals that produces milk to feed young offspring mammals get their name from the latin word mamma breast the mammary glands are arranged in organs such as the breasts in primates for example humans and chimpanzees the udder in ruminants for example cows goats and deer and the dugs of other animals for example dogs and cats. Epithelial cells are defined as cells or tissue of the epithelium a thin layer of tissue that covers or lines the surface of tubes or cavities within the body. Biology of the mammary gland provided by the national institute of health labarge lab.

Definition of epithelial cells. Review of the human mammary epithelial cell hmec culture system last revised january 2003 procedures. In these structures there are two main cell types. Atcc stands ready to support our customers needs during the coronavirus pandemic.

Additional websites of interest for mammary gland biology. Viability at least 70 500 000 viable cells vial capable of at least 16 population doublings mycoplasma. When epithelial cells become malignant become cancerous they form tumors that are referred to as carcinomas. Not detected bacteria yeast and othe.

An overview of growth aging senescence and immortality. Atcc primary cell solutions offers epithelial cells isolated from human breast bronchi trachea and small airways cornea prostate and kidneys. Not detected hepatitis b. Breast cancer is the most common cancer in women and a leading cause of cancer related deaths for women worldwide.

The inner luminal cells surrounded by basal myoepithelium. These cells types are distinct and are the precursors to various forms of breast cancer. Not detected hepatitis c. Around 80 of cancers in the human.

The mcf10a human mammary epithelial cell line is a widely used in vitro model for studying normal breast cell function and transformation. The majority of breast cancers originate in the lobular or ductal cells of the milk producing glands. Human mammary epithelial cells were obtained from a healthy individual undergoing reduction.