Human Bone Marrow Stromal Cells

Bone marrow is a semi solid tissue found within the spongy or cancellous portions of bones.

Human bone marrow stromal cells.

Bone marrow stromal cells bmscs contains a subset of skeletal stem cells sscs that are multipotent capable of forming cartilage bone hematopoiesis supportive stroma and marrow adipocytes. Cd2 t lymphocytes obtained from either the donor of bone marrow stromal cells bmscs or a third party were cultured in mixed lymphocyte reactions mlrs with either allogeneic dendritic cells dcs or peripheral blood lymphocytes pbls. Human bone marrow stromal cells derived in acf medium catalog 70071 using the mesencult acf culture kit catalog 05449 differentiate to a adipocytes oil red o staining b chondrocytes alcian blue and nuclear fast red staining and c. When autologous or allogeneic bmscs were added back to t c.

Sscs have been identified as pericytes cells on the abluminal side of marrow sinusoids and have demonstrated the ability to self renew. In birds and mammals bone marrow is the primary site of new blood cell production or haematopoiesis. The most common stromal cells include fibroblasts and pericytes the term stromal comes from latin stromat bed covering and ancient greek στρῶμα. Stromal cells are connective tissue cells of any organ for example in the uterine mucosa endometrium prostate bone marrow lymph node and the ovary they are cells that support the function of the parenchymal cells of that organ.