Hiv Treated With Stem Cells

After the stem cell treatment which involved replacing the patient s white blood cells with hiv resistant versions the patient was deemed as in remission.

Hiv treated with stem cells.

In this case however there was a second goal. He had chemotherapy to treat the hodgkin s cancer and in addition stem cells were implanted into the patient from a donor resistant to hiv leading to both his cancer and hiv going into remission. Hiv treatment has been stymied because reservoirs of infected cells have remained latent or in hiding in the bone marrow of patients and can later reactivate. Uk patient free of hiv after stem cell treatment reports bbc news.

Doctors report that a man with hiv who was given a stem cell transplant to treat his blood cancer has no detectable signs of hiv 18 months after stopping anti hiv treatment. Treatment with anti virals. He looked for a donor with a specific genetic mutation that made them practically immune to hiv. The twist was tim s bone marrow donor was immune to hiv.

Receiving stem cells from this donor it turned out not only treated mr. To cure the patient s hiv. He received a stem cell transplant from a donor. Stem cell transplants are an established treatment for the cancer.

The man had hodgkin lymphoma a cancer of the lymphatic system a key part of our immune system. Brown s leukemia but. To treat his leukemia his doctors wanted to wipe out his immune system with radiation and chemotherapy and then rebuild it with donated stem cells. This is one of the standard bone cancer treatments.

But in order to treat the lymphoma with stem cells doctors needed to find a donor who was resistant to his other condition hiv the virus that causes aids. As the donor has a very rare genetic mutation ccr5 delta 32 that makes them hiv resistant the stem cells sent the hiv into remission with only a mild reaction from the treatment.